Clinical Observation and Immunological Functions on Kangdu Buxin Capsule in Treatment of Viral Myocarditis

LV Li-xun; LI Jie; MA Hui-xia; WU Fan-wu; BAO Ju-tai

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Clinical Observation and Immunological Functions on Kangdu Buxin Capsule in Treatment of Viral Myocarditis

更新时间：2024-01-04

- Clinical Observation and Immunological Functions on Kangdu Buxin Capsule in Treatment of Viral Myocarditis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 24, Pages: 200-202(2011)
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- Published：2011
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LV Li-xun, LI Jie, MA Hui-xia, et al. Clinical Observation and Immunological Functions on Kangdu Buxin Capsule in Treatment of Viral Myocarditis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 200-202.
DOI：

LV Li-xun, LI Jie, MA Hui-xia, et al. Clinical Observation and Immunological Functions on Kangdu Buxin Capsule in Treatment of Viral Myocarditis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 200-202. DOI：

摘要

目的: 观察抗毒补心胶囊治疗病毒性心肌炎的临床效果及其对机体的免疫调节作用。方法: 60例病毒性心肌炎患者随机分为治疗组、对照组

治疗组口服抗毒补心胶囊治疗

4粒/次

4次/d

口服

对照组用常规西药治疗

静滴极化液:10%葡萄糖注射液 500 mL+胰岛素 8 U+10%氯化钾 10 mL

每天 1 次;口服辅酶 Q10 20 mg

维生素 C 片 0.2 g

每天 3 次

疗程4周。2组均酌情使用一般抗心律失常药。分别观察其临床疗效

肌酸肌酶(CK)及其同工酶(CK-MB)

白细胞介素(IL-2)及肿瘤坏死因子(TNF-α)的变化。结果 :治疗组、对照组有效率分别为93.3％和76.7％

二者比较差异有统计学意义(P<0.05);治疗后

2组患者心肌酶、TNF-α及IL-2水平下降

治疗前后比较差异有统计学意义(P<0.05);治疗组与对照组相比

差异亦有统计学意义(P<0.05)。结论 :抗毒补心胶囊治疗病毒性心肌炎效果较好

且可调节机体的免疫功能。

Abstract

Objective : To observe the clinical efficiency and immunological regulation of Kangdu Buxin capsule in treatment of viral myocarditis. Method : Sixty patients with VMC were randomly divided into treatment group and control group

treatment group was treated with Kangdu Buxin capsule and control group was treated with conventional therapy for 4 weeks. Clinical efficiency and improvement of CK

CK-MB

TNF-α

IL-2 were observed. Result :The total effective rates of treatment and control group were 93.3％ and 76.7％ with significant difference(P<0.05). After treatment

the levels of CK

CK-MB

IL-2

TNF-α were decreased in two groups(P<0.05).Compared with control group

statistical difference was also observed (P<0.05). Conclusion : Kangdu Buxin capsule is effective in the treatment of viral myoearditis

and it also has a good regulation effect on the immune function.

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Related Author

YAO Yan-yan

XU Jia

BAO Ju-tai

WANG Chun-yan

LV Li-xun1

YAO Yan-yan1

XU Jia1

MA Hui-xia2

Related Institution

School of Pharmay Hebei United University

College of Traditional Chinese Medicine,Hebei United University

Sichuan Academy of Medical Sciences, Sichuan People's Hospital

Chengdu Fifth People's Hospital Chengdu

First Affiliated Hospital of Xinxiang Medical College

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