Release Evaluation for Spray Film of Extract from Galla Chinensis
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Release Evaluation for Spray Film of Extract from Galla Chinensis
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 6, Pages: 27-29(2012)
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Published:2012
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JIN Lin, WANG Jin-yu, TONG Yan, et al. Release Evaluation for Spray Film of Extract from Galla Chinensis[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(6): 27-29.
DOI:
JIN Lin, WANG Jin-yu, TONG Yan, et al. Release Evaluation for Spray Film of Extract from Galla Chinensis[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(6): 27-29.DOI:
Release Evaluation for Spray Film of Extract from Galla Chinensis
Objective: To establish a determination method of in vitro release for spray film of extract from Galla Chinensis
and investigate its in vitro release characteristics. Method: With gallic acid as index
modified Franz diffusion cell was chosen with semi-permeable membrane as in vitro permeability barrier
the content of gallic acid was determined by HPLC and in vitro release of gallic acid was calculated. Result: Affect of penetration enhancers on release effect of this spray film was not obvious
equation of in vitro release model fitted best with Kinetic equation. Conclusion: This spray film had characteristics of good release and Kinetic equation
it could be achieved a better release effect without penetration enhancers.