Objective: To study on application of liquid mixture density formula in preparating of decoction agent. Method: Liquid mixture density formula was used to investigate different preparation process and conditions (concentration

experiment design

different extraction rate of slices

different density of excipients) by combining with application method and examples. Result: Liquid mixture density formula could foresee result of preparation decoction agent

improve accuracy of operation. Conclusion: Liquid mixture density formula could be applied and extended in preparation of decoction agent widely.