Objective: To evaluate the clinical curative effect of Peiben Quyu granules in treat ing chronic renal failure and the microinflammation caused by spleen and kidney deficiency and bturbid damp stasisi. Method: Eighty chronic renal failure patients with spleen and kidney deficiency and turbid damp and stasis were randomly divided into two groups

40 cases as treatment group

40 cases as control group; treatment group was given Peiben Quyu granules

control group was given western medicine like Ketosteril Pian etc. Result: The total efficacy rate was 77.5% in the treatment group and 52.5% in the control group

the curative effect of the index of renal function and microinflammation in the treatment group was better than the control group. There was significant difference between the two groups (P<0.05). Conclusion: Peiben Quyu granules has a good curative effect on treating chronic renal failure with the spleen and kidney deficiency and turbid damp and stasis.