Study on the Mechanism of Anti-fatigue Effect by

LIU Xiao-bo; GUO Mei-xian; LI Wen; WANG Shou-zhi; GUO Rong-qing; LUO Shi-jun; LI Shuang-cui

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Study on the Mechanism of Anti-fatigue Effect by

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- Study on the Mechanism of Anti-fatigue Effect by
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 24, Pages: 168-170(2011)
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- Published：2011
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LIU Xiao-bo, GUO Mei-xian, LI Wen, et al. Study on the Mechanism of Anti-fatigue Effect by [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 168-170.
DOI：

LIU Xiao-bo, GUO Mei-xian, LI Wen, et al. Study on the Mechanism of Anti-fatigue Effect by [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 168-170. DOI：

摘要

目的 :研究鸡肉参的抗疲劳作用机制。方法 :采用对照组及鸡肉参乙醇提取物低、中、高(1.6

3.2

6.4 g·kg-1·d-1)3个剂量组对小鼠ig 24 d后进行游泳实验

并对血乳酸(LD)、乳酸脱氢酶(LDH)、血清尿素氮(BUN)、肝糖原、肌糖原等进行了测试。结果: 其中NS组的肝糖原含量(23.26±15.40)mg·g-1

肌糖原含量(0.65±0.32)mg.g-1

LDH(8 652±2 924)U·L-1

BUN (6.72±1.19)mmol·L-1

LD(9.66±3.78)mmol·L-1。与NS组比较

鸡肉参可提高肝糖原(57.42±21.49)mg·g-1、肌糖原(1.23±0.47)mg·g-1的含量(P<0.01

P<0.05)

提高LDH(11 792±2 455)U·L-1的活力(P<0.01)

同时降低BUN(4.02±1.19)mmol·L-1和LD(11.84±6.45)mmol·L-1的水平(P<0.01)。结论: 鸡肉参具明显的抗疲劳作用

其抗疲劳作用机制主要是通过影响LD

LDH

BUN

肝糖原

肌糖原。

Abstract

Objective : To study the mechanism of anti-fatigue effect by Incarvillea mairei(le’vl) Geireson. Methods : The anti-fatigue function of the ethanol extract of I. mairei was determined by swimming test in mice

and blood lactic acid (LD)

serum lactale dehydrogenase (LDH)

serum urea nitrogen (BUN)

muscle glycogen and liver glycogen were detected. Results : I. mairei could increase the liver glycogen and muscle glycogen content

and enhance the activity of lactic dehydrogenase

while decrease the blood urea nitrogen and blood lactic acid. Conclusion : The I. mairei may improve anti-fatigue ability by influencing blood LD

serum LDH

serum BUN

muscle glycogen and liver glycogen.

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