Optimization of Forming Technology of Sanyu Ointment
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Optimization of Forming Technology of Sanyu Ointment
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 7, Pages: 17-19(2012)
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Published:2012
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YIN Hua, ZHOU Ai-zhen, WANG Zhi-qing. Optimization of Forming Technology of Sanyu Ointment[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 17-19.
DOI:
YIN Hua, ZHOU Ai-zhen, WANG Zhi-qing. Optimization of Forming Technology of Sanyu Ointment[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 17-19.DOI:
Optimization of Forming Technology of Sanyu Ointment
Objective: To optimize forming technology of Sanyu ointment. Method: Emulsion-type matrix was screened in different ratio;Using appearance and stability as evaluation indexes
forming technology of Sanyu ointment was optimized by orthogonal test. Result: Optimal forming technology was:Took drug concentrated liquid was added triethanolamine
glycerol and ethylparaben heating to 85 ℃ as aqueous phase;Took stearic acid
glyceryl monostearate
liquid paraffin
white vaselin and lanolin heating to melt at 85 ℃as oil phase. Then added oil phase to aqueous phase with small-streams flowing
stirring at a speed of 550 r·min-1 to cool completely. Conclusion: Optimized forming technology was reasonable and feasible
which could produce stable preparation and was suitable for industrial production.