Preparation and Permeability of Arnebiae Radix Ointment
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Preparation and Permeability of Arnebiae Radix Ointment
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 21, Pages: 36-38(2011)
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Published:2011
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SU Yu-ke. Preparation and Permeability of Arnebiae Radix Ointment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 36-38.
DOI:
SU Yu-ke. Preparation and Permeability of Arnebiae Radix Ointment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 36-38.DOI:
Preparation and Permeability of Arnebiae Radix Ointment
Objective: To optimize formulation of Arnebiae Radix ointment. Method: An in vitro model of transdermal permeation was established. In vitro penetration rate of Arnebiae Radix ointment was examined by HPLC
permeation curve was fitted to the Higuchi equation. Result: O/W ointment of Arnebiae Radix had the best penetration rate in all the five formulations
average J value was up to 14.797 μg·h-1·cm-2 calculated with shikonin. Besides
its cumulative permeation curve fitted to the Higuchi equation best. Conclusion: Optimize formulation was O/W ointment.