Optimization of Extraction Technology for Jiegu Zhitong Tablet

YI Yan-kui; DENG Hong-zhu; YU Yang

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Optimization of Extraction Technology for Jiegu Zhitong Tablet

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- Optimization of Extraction Technology for Jiegu Zhitong Tablet
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 2, Pages: 42-44(2012)
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- Published：2012
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YI Yan-kui, DENG Hong-zhu, YU Yang. Optimization of Extraction Technology for Jiegu Zhitong Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 42-44.
DOI：

YI Yan-kui, DENG Hong-zhu, YU Yang. Optimization of Extraction Technology for Jiegu Zhitong Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 42-44. DOI：

摘要

目的: 探讨接骨止痛片中骨碎补、续断、红花、土蟞虫醇提取工艺。方法: 采用正交试验法

对接骨止痛片主要成分的醇提取条件进行优选。以醇浸膏得率

柚皮苷提取量为考查指标

对乙醇体积分数、加醇量、提取时间进行了优选。结果: 最佳醇提取工艺为药材加80%乙醇回流提取2次

第1次加6倍量提取2 h

第2次加5倍量提取1.5 h。结论: 接骨止痛片的醇提工艺合理

稳定。

Abstract

Objective: To investigate alcohol extraction technology of Drynaria fortunei

Radix dipsaci

Flos carthami

Eupolyphaga seu steleophaga from Jiegu Zhitong tablet. Method: Orthogonal method was used to optimize alcohol extraction conditions of main ingredients from Jieguzhitong tablet.Took yield of alcohol extracts

extraction of naringin as indexes to optimize ethanol concentration

alcohol volume

extraction time. Result: Optimum extraction technology was as follows:reflux extracted 2 times with 80% ethanol

the first time extracted 2 h with 6 times the amount of 80% ethanol

then extracted 1.5 h with 5 times in second time. Conclusion: The extraction technology of Jiegu Zhitong tablet was stable and feasible.

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Related Institution

Faculty of Medicine,Beihua University

Henan University of Traditional Chinese Medicine

Zhoukou Hospital of Traditional Chinese Medicine

Chinese People’s Liberation Army 150 Central Hospital,Louyang

Tianjin Key Laboratory Industrial Microbiology,College of Bioengineering,Tianjin University of Science and Technology

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