Effect of Yunmuxiang on Gastric Emptying and Intestinal Propulsion of Mice
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Effect of Yunmuxiang on Gastric Emptying and Intestinal Propulsion of Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 2, Pages: 136-139(2012)
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Published:2012
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ZHANG Meng, GUO Jian-sheng, WANG Xiao-juan, et al. Effect of Yunmuxiang on Gastric Emptying and Intestinal Propulsion of Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 136-139.
DOI:
ZHANG Meng, GUO Jian-sheng, WANG Xiao-juan, et al. Effect of Yunmuxiang on Gastric Emptying and Intestinal Propulsion of Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 136-139.DOI:
Effect of Yunmuxiang on Gastric Emptying and Intestinal Propulsion of Mice
Objective: To study the effect of 3 kinds of extract of Yunmuxiang on gastric emptying and intestinal propulsion of mice
and to find the material basis of Yunmuxiang which affact gastric emptying and intestinal propulsion of mice. Method: Using modified determination of content of phenol red to observe the effect of 3 kinds of extract of Yunmuxiang on gastric emptying and intestinal propulsion of mice in normal state
hyperthyroidism state caused by neostigmine
inhibiting state caused by atropine. Result: Volatile oil of Yunmuxiang could significant decrease gastric emptying rate of phenol red of normal mice(P<0.01)
could significantly improve gastric emptying rate of phenol red in the state of inhibition caused by atropine(P<0.01)
could significantly decrease gastric emptying rate of phenol red in the state of hyperthyroidism caused by neostigmine(P<0.05). Conclusion: The extract of Yunmuxiang can inhibit gastric emptying of normal mice
can improve gastric emptying of mice in the state of inhibition caused by atropine
antagonistise gastric emptying and intestinal propulsion of phenol red in the state of hyperthyroidism caused by neostigmine. Volatile oil and low-polar substances are more likely to the material basis of Yunmuxiang which affact gastrointestinal tract of mice.
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Related Institution
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Institute of Traditional Chinese Medicine(TCM),Sichuan Academy of TCM Sciences (The Second Hospital of Sichuan Province of TCM)
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Institute of Basic Theory of Traditional Chinese Medicine(TCM),China Academy of Chinese Medical Sciences