Optimization of Ultrasound Extraction Process of Total Flavonoids from by Response Surface Methodology
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Optimization of Ultrasound Extraction Process of Total Flavonoids from by Response Surface Methodology
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 20, Pages: 17-20(2011)
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Published:2011
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JIANG Zhi-hua, YU Li-chao, FENG Zi-wang, et al. Optimization of Ultrasound Extraction Process of Total Flavonoids from by Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 17-20.
DOI:
JIANG Zhi-hua, YU Li-chao, FENG Zi-wang, et al. Optimization of Ultrasound Extraction Process of Total Flavonoids from by Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 17-20.DOI:
Optimization of Ultrasound Extraction Process of Total Flavonoids from by Response Surface Methodology
Objective: To optimize optimum ultrasound extraction process of total flavonoids from Agrimania pilosa. Method: With yield of total flavonoids as index
ethanol concentration
ultrasound temperature and material-liquid ratio were optimized by response surface methodology (RSM). Result: Effect factors on extraction rate of total flavonoids with the order of follows: material-liquid ratio
ultrasound temperature
ethanol concentration. The optimal extraction conditions were ethanol concentration was 72%
material-liquid ratio of 1 ∶25
extraction temperature was 60 ℃
extraction time was 20 min. Under these conditions
yield of total flavonoids reached 9.02 mg·g-1
which was agreed with model prediction. Conclusion: This extraction process of total flavonoids from A. pilosa by ultrasound-assisted was stable and reliable.