Systematic Evaluation of Adverse Drug Reactions of Xiyanping Injection From Documents

WANG Yan-ping; JIAO Kai; HE Zhong-fang

您当前的位置：

首页 >

文章列表页 >

Systematic Evaluation of Adverse Drug Reactions of Xiyanping Injection From Documents

更新时间：2024-01-04

- Systematic Evaluation of Adverse Drug Reactions of Xiyanping Injection From Documents
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 24, Pages: 236-239(2011)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2011
- 稿件说明：
移动端阅览
WANG Yan-ping, JIAO Kai, HE Zhong-fang. Systematic Evaluation of Adverse Drug Reactions of Xiyanping Injection From Documents[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 236-239.
DOI：

WANG Yan-ping, JIAO Kai, HE Zhong-fang. Systematic Evaluation of Adverse Drug Reactions of Xiyanping Injection From Documents[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 236-239. DOI：

摘要

目的 :了解喜炎平注射剂不良反应的发生情况及其相关因素

探索药品上市后不良反应再评价的方法。方法 :收集静脉滴注喜炎平注射剂不良反应文献资料

并分为同期对照临床研究、不良反应监测或病案系列报告、个案或典型病例报告3类

进行归类、整理、分析。结果 :不同研究方法显示喜炎平注射剂平均不良反应发生率为2.02%

不良反应类型以变态反应为主

且发现多种说明书记载以外的罕见类型;在121例个案报道中

0~10岁儿童是高发人群

不良反应发生率为45.45%;过敏性体质或有过敏史患者易发生不良反应

占10.74%;不良反应发生时间多为用药后30 min内

占54.55%;在不良反应治疗与转归中

除1例有基础疾病与过敏史患者死亡外

其余均经治疗痊愈。结论 :规范喜炎平注射剂的临床合理使用

尽量减少不良反应的发生;针对有效可利用的文献报告情况

建议临床研究者应尽量详细报告所研究药物的不良反应情况

提高文献质量。

Abstract

Objective : To find out the occurrence rate of adverse drug reactions (ADR) following the intravenous administration of Xiyanping Injection and to understand the relative factors such as the type and constitution of ADR. To preliminarily explore the methods for reevaluation of the drug after marketing. Method : A comprehensive collection of literature was classified into 3 categories

synchronous clinical study

monitoring of ADR and analysis of medical records

as well as individual or typical case reports. Result: Different study methods indicated that the mean occurrence rate of ADR in Xiyanping Injection was2.02%;ADR manifested mainly as anaphylactic reaction. In addition

a variety of rare types of ADR was discovered

which was not indicated in the instructions of the product. Conclusion: The ADR of Xiyanping injection represented mainly as anaphylactic reaction

especially with anaphylactic shock.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰