Research on the Best Compatibility Proportion of Rhizoma Coptidis and Fructus Forsythiae’s Anti-inflammatory Effect
|更新时间:2024-01-04
|
Research on the Best Compatibility Proportion of Rhizoma Coptidis and Fructus Forsythiae’s Anti-inflammatory Effect
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 21, Pages: 113-115(2011)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2011
稿件说明:
移动端阅览
YU Tian-yu, ZHANG Zhen-qiu, LI Wei-ming, et al. Research on the Best Compatibility Proportion of Rhizoma Coptidis and Fructus Forsythiae’s Anti-inflammatory Effect[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 113-115.
DOI:
YU Tian-yu, ZHANG Zhen-qiu, LI Wei-ming, et al. Research on the Best Compatibility Proportion of Rhizoma Coptidis and Fructus Forsythiae’s Anti-inflammatory Effect[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 113-115.DOI:
Research on the Best Compatibility Proportion of Rhizoma Coptidis and Fructus Forsythiae’s Anti-inflammatory Effect
Objective: Explore the best compatibility proportion of rhizoma coptidis and Fructus Forsythiae’s anti-inflammatory effect. Method: Research the effect of each proportion of rhizoma coptidis and Fructus Forsythiae to the swelling of rat’s toe caused by injecting egg albumin. Give each groups berberine
forsythia
the ratio of the drug
aspirin
and saline.Respectively
5
30 min
1
2
4
6 h measure toe volume
calculate swelling rate. Establish an HPLC method for simultaneous determination of indicator ingredient of each proportion. Looking for links between them. Result: Berberine
forsythia proportion of the compatibility have an effect on inhibition of swelling. By analyzing the compatibility proportion of rhizoma coptidis and fructus forsythiae’s is 1 ∶1
it has the lowest swelling rate
therefore
has the most effective anti-inflammatory. There is the highest composite score when the compatibility proportion of rhizoma coptidis and fructus forsythiae’s is 1 ∶1. Conclusion: The best compatibility proportion of rhizoma coptidis and fructus forsythiae’s anti-inflammatory effect is 1 ∶1.