Refining Technology of Dange Dropping Pills with Macroporous Resin

ZHENG Ya-nan; LV Yuan-shan; REN Tao

您当前的位置：

首页 >

文章列表页 >

Refining Technology of Dange Dropping Pills with Macroporous Resin

更新时间：2024-01-04

- Refining Technology of Dange Dropping Pills with Macroporous Resin
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 22, Pages: 17-20(2011)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2011
- 稿件说明：
移动端阅览
ZHENG Ya-nan, LV Yuan-shan, REN Tao. Refining Technology of Dange Dropping Pills with Macroporous Resin[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 17-20.
DOI：

ZHENG Ya-nan, LV Yuan-shan, REN Tao. Refining Technology of Dange Dropping Pills with Macroporous Resin[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 17-20. DOI：

摘要

目的: 对大孔树脂富集纯化丹葛滴丸的工艺条件及参数进行优化。方法: 以丹酚酸B、葛根素含量为指标

考察大孔树脂对其的吸附性能和洗脱参数。结果: 最终确定纯化工艺为采用AB-8型大孔树脂

树脂用量为药材2倍

树脂径高比1 ∶6

流速1 BV·h-1上样

5 BV pH 4盐酸水溶液洗脱弃去

3 BV 50%乙醇洗脱收集。结论: 用大孔树脂对丹葛滴丸进行精制

工艺简单可行

分离效果好

减少了纯化固形物的量

从而降低服用量。

Abstract

Objective: To optimize purification technical conditions and parameters of Dange dropping pills by macroporous resin. Method: Investigated adsorption property and elution parameters of macroporous resins by using the content of salvianolic acid B and puerarin as indexes. Result: Finally

purification technology was determined as follows:AB-8 was optimal resin type.Capacity of AB-8 macroporous adsorptive resin was as much as 2 times to sample load(φ ∶h=1 ∶6)

flow rate of sample was 1 BV·h-1

5 BV amount of distilled hydrochloric acid solution(pH 4)used for eluting

and 3 BV amount of 50% ethanol as desorption solvent. Conclusion: Optimum refining process of Dange dropping pills by macroporous adsorption resin was simple and feasible with good effect of separation.It could decrease the yield of extract

and dose of drug was decreased.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Salvianolic Acid B Combined with Puerarin on Pyroptosis of SH-SY5Y Cells Injured by Oxygen-glucose Deprivation/Reoxygenation

Standard of Quality Control of Mailuotong Jiaonang

Grade Evaluation of Salviae Miltiorrhizae Radix et Rhizoma Decoction Pieces Based on Relative Quality Constant

Quality Control of Salvianolic Acids Reference Extract

Protective Effect of Salvianolic Acid B on Arsenic Trioxide-induced HepaRG Human Hepatocyte Injury

Related Author

TU Shuxin

WANG Yan

HE Xiaoli

TAN Qin

SHEN Ting

JIN Fang

GUO Qing

YAO Zhong-qing

Related Institution

Institute of Medicinal Plant Development，Chinese Academy of Medical Sciences and Peking Union Medical College

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

School of Pharmacy，Hebei University

Jiangxi University of Traditional Chinese Medicine

National Institutes for Food and Drug Control

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰