Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion
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Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 14, Pages: 237-239(2011)
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Published:2011
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LI Hui, CHEN Jian-she. Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(14): 237-239.
DOI:
LI Hui, CHEN Jian-she. Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(14): 237-239.DOI:
Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion
Objective: To explore the mechanism of Qingong capsule on uterine hemorrhage after medicine induced abortion. Method : Induced abortion models were made with pregnant rats drenched with mifeprisrone and misoprostol. The level of estrogen in blood
contents of nitric oxide (NO) and the activity of nitric oxide synthase (NOS) in uterus homogenate of the rats after medicine induced abortion in every group were measured and compared. The action of Qingong (1.9
3.8 g ·kg-1 ·d-1) capsule on medicine induced abortion was observed. Result : The Estrogen content in uterus homogenate Qingong capsule group was obviously higher than that in model group
and the content of NO and NOS were obviously lower than those in mdoel group. Conclusion : The mechanism of Qingong capsule on uterine haemorrhagia after medicine induced abortion may be related with improving the level of estrogen in blood and reducing the contents of NO and NOS in uterus tissue
thus it has better preventive and therapeutic effects on vaginal bleeding after medical abortion.
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