Screening of Formative Excipients for Guizhi Granule

ZHANG Wei-bing; YANG Bao-yan

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Screening of Formative Excipients for Guizhi Granule

更新时间：2024-01-04

- Screening of Formative Excipients for Guizhi Granule
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 20, Pages: 45-47(2011)
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- Published：2011
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ZHANG Wei-bing, YANG Bao-yan. Screening of Formative Excipients for Guizhi Granule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 45-47.
DOI：

ZHANG Wei-bing, YANG Bao-yan. Screening of Formative Excipients for Guizhi Granule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 45-47. DOI：

摘要

目的: 优选桂枝颗粒的成型辅料。方法: 考察不同种类和比例的辅料对桂枝颗粒成型性、溶化性和吸湿性的影响

并用综合评分法筛选出制备桂枝颗粒的最优辅料及辅料比例。结果: 制备桂枝颗粒的最优辅料为糊精和乳糖

两者使用比例为1 ∶1。结论: 采用该方法制成的桂枝颗粒成型性、溶解性好

不容易吸湿

效果理想。

Abstract

Objective: To optimize the formative excipients for Guizhi granule. Method: Effects of different types and ratios excipients on the formation

moisture absorption and relative critical humidity of Guizhi granule were examined

and the optimal excipients as well as formula were selected by adoption of the comprehensive scoring method. Result: The optimal excipient for preparation of Guizhi granule were dextrin and lactose

and the ratio of between the two was 1 ∶1. Conclusion: The Guizhi granule thus prepared is ideal:good in shape

easy to dissolve and not liable to moisture absorption.

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