Randomized Controlled Trials of Tangmaikang Particles Combined with Captopril on Diabetic Nephropathy
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Randomized Controlled Trials of Tangmaikang Particles Combined with Captopril on Diabetic Nephropathy
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 18, Pages: 251-253(2011)
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Published:2011
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ZHANG Yu-mei, KANG Li. Randomized Controlled Trials of Tangmaikang Particles Combined with Captopril on Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 251-253.
DOI:
ZHANG Yu-mei, KANG Li. Randomized Controlled Trials of Tangmaikang Particles Combined with Captopril on Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 251-253.DOI:
Randomized Controlled Trials of Tangmaikang Particles Combined with Captopril on Diabetic Nephropathy
Objective: To observe the clinical efficacy of Tangmaikang particles combined with captopril on diabetic nephropathy (DN). Method: 160 patients were randomly divided into two groups which were the observation group and the control group. The control group received captopril treatment
25 mg/time
three times/d. And the observation group was received Tangmaikang particles 5 g
tid. combined with captopril treatment
25 mg
tid. BUN
SCr and 24 h urinary protein were observed after 4 weeks treatment. Result: Two groups of patients with BUN
SCr
24 h urinary protein in pre-treatment was no significant difference. After treatment 4 weeks
the observation group compared with the same group before treatment
efficacy was significant difference (P<0.05); the control group compared with the same group before treatment
24 h urinary protein was significant difference in external (P<0.05)
BUN
SCr
while improving
but not statistically significant; compared the two groups after treatment
the effect was significant difference (P<0.05). Conclusion: Tangmaikang particles combined with captopril on treatment of DN was better than captopril alone.
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