Study on Refining Process Screening of Huanglian Jiedu Decoction by Macroporous Resin Based on Pharmacodynamical Test
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Study on Refining Process Screening of Huanglian Jiedu Decoction by Macroporous Resin Based on Pharmacodynamical Test
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 18, Pages: 1-5(2011)
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Published:2011
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ZHU Hua-xu, LI Huan, GU Xiao-ying, et al. Study on Refining Process Screening of Huanglian Jiedu Decoction by Macroporous Resin Based on Pharmacodynamical Test[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 1-5.
DOI:
ZHU Hua-xu, LI Huan, GU Xiao-ying, et al. Study on Refining Process Screening of Huanglian Jiedu Decoction by Macroporous Resin Based on Pharmacodynamical Test[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 1-5.DOI:
Study on Refining Process Screening of Huanglian Jiedu Decoction by Macroporous Resin Based on Pharmacodynamical Test
Objective: To compare pharmacological activity and chemical composition changes of water extract from Huanglian Jiedu Decoction (HLJDT) after refined by 10 different Macroporous Resins. Investigated optimization principle of refining process by resin from traditional Chinese medicine compound
provided basis to refining and separation of traditional Chinese medicine compound prescription. Method: Ten different polarity type of polystyrene Macroporous Resins were selected to refine the water extract from HLJDT. Took activity tracking filter of rat adrenal medulla pheochromocytoma PC-12 cell
determined the effect of water extract and refined material to low-sugar of DMEM and the oxygen-glucose deprivation injury of cobalt chloride-induced PC-12cells by MTT. The content of six index ingredients (berberine
palmatine
baicalin
baicalein
wogonin and geniposide) were detected by RP-HPLC. Result: The results show:the refined material of water extract by X-5-type Macroporous Resin was better able to retain the existing ratio of each component in HLJDT
and the pharmacodynamic effects consistent with HLJDT. Conclusion: This study settled experimental basis to clinical improved formulations and of industrial production of HLJDT.
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Investigation of Adsorption and Desorption Properties of Total Ginsenosides on Anion-exchange Resins and Its LC-MS Analysis
LCMS-IT-TOF Analysis of Retention Behavior of Sanguisorbae Radix Components on D101 Macroporous Resin and Polyamide Resin
Optimization of Purification Process of Total Alkaloid Extract of Berberis dictyophylla Cortex by Macroporous Resin and Investigation of Its Quality Standard
Recovery and Utilization of Alkaloids in Processing Wastewater of Aconiti Radix
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