Objective: To prepare Awei Huapigao emplastrum by using acrylate pressure sensitive adhesive as matrix

and preliminary optimized of preparation technology. Method: Optimized prescription of emplastrum by determined hold adhesion and 180° peel strength and combined appearance index. Result: Optimized prescription of Awei Huapigao emplastrum was as follows: water 0.40 g

ethanol 0.30 g

acryliate pressure sensitive adhesive 4.50 g

and acrylicresin 0.30 g. Mean 180° peel strength was 0.33 kN·m-1

mean hold adhesion was 15.45 h. Conclusion: Appearance index of the emplastrum was fine.