Protein Binding Percentage of Dehydroandrographolide in Different Plasma Samples by Ultrafiltration
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Protein Binding Percentage of Dehydroandrographolide in Different Plasma Samples by Ultrafiltration
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 21, Pages: 57-59(2011)
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Published:2011
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WU Yang, ZHANG Ying-feng. Protein Binding Percentage of Dehydroandrographolide in Different Plasma Samples by Ultrafiltration[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 57-59.
DOI:
WU Yang, ZHANG Ying-feng. Protein Binding Percentage of Dehydroandrographolide in Different Plasma Samples by Ultrafiltration[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 57-59.DOI:
Protein Binding Percentage of Dehydroandrographolide in Different Plasma Samples by Ultrafiltration
Objective: To study protein binding percentage of dehydroandrographolide in different plasma samples. Method: The protein binding rates of dehydroandrographolide in BSA plasma samples
human plasma samples and rat plasma samples were determined by ultrafiltration and HPLC. Result: The plasma protein binding rate of dehydroandrographolide with BSA
human plasma
rat plasma were (71.50±1.50)%
(79.91±2.51)%
(82.41±2.05)% respectively. Conclusion: The binding of dehydroandrographolide with plasma is middle degree.