Effect of Habitat Strychnos Pill Combined with Leflunomide for Treatment of Rheumatoid Arthritis

SUN Zhi-xia

您当前的位置：

首页 >

文章列表页 >

Effect of Habitat Strychnos Pill Combined with Leflunomide for Treatment of Rheumatoid Arthritis

更新时间：2024-01-04

- Effect of Habitat Strychnos Pill Combined with Leflunomide for Treatment of Rheumatoid Arthritis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 14, Pages: 272-274(2011)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2011
- 稿件说明：
移动端阅览
SUN Zhi-xia. Effect of Habitat Strychnos Pill Combined with Leflunomide for Treatment of Rheumatoid Arthritis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(14): 272-274.
DOI：

SUN Zhi-xia. Effect of Habitat Strychnos Pill Combined with Leflunomide for Treatment of Rheumatoid Arthritis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(14): 272-274. DOI：

摘要

目的: 观察中药生地马钱丸配合来氟米特治疗类风湿性关节炎(RA)的疗效及安全性。方法 :90例RA患者随机分为两组

对照组40例患者给予来氟米特口服以及对症治疗;治疗组50例在对照组治疗的基础上口服生地马钱丸

3 g/次

3次/d。两组疗程均为6个月。监测治疗前后临床疗效指标的变化及药物的不良反应。结果 : 治疗组总有效率显著高于对照组(P＜0.05);两组在关节疼痛数、关节压痛积分、关节肿胀积分、晨僵时间及20 m步行时间等及血沉(ESR)

慢反应物质(CRP)方面均与用药前比较有显著改善(P＜0.05或P＜0.01)

且治疗组均优于对照组(P<0.05

P<0.01);口服生地马钱丸未发生明显的不良反应。结论 : 生地马钱丸配合来氟米特治疗RA疗效优于单用来氟米特

且安全性好。

Abstract

Objective: To observe the efficacy and safety of Habitat Strychnos pill Combined with leflunomide for the treatment of rheumatoid arthritis (RA). Method: Ninety cases of RA were randomly divided into 2 groups

control group(40 cases) given leflunomide with oral

as well as symptomatic treatment; the treatment group (50 cases)received oral Chinese medicine Habitat Strychnos pill on the basis of therapy in the control group. The course of treatment was 6 months. Before and after treatment changes in indicators of clinical efficacy and adverse drug reactions were monitored. Result: The treatment group was significantly higher than the control group for the total effective rate (P<0.05). Compared with pre-treatment

the treatment significantly improved efficacy in the number of joint pain

joint tenderness score

joint swelling score

morning stiffness time and 20 m walking time

ESR

CRP (P<0.05 or P <0.01). Oral medicine pills habitat Strychnos did not show obvious side effects. Conclusion :Habitat Strychnos pill with leflunomide for the treatment of RA is more effective than leflunomide alone

and the safety is good.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Quercetin on Cuproptosis in Rheumatoid Arthritis Rats and Its Mechanism via SLC31A1/FDX1 Pathway

Chinese Medicine Intervenes in NLRP3 Inflammasome in Treatment of Bone and Joint Diseases： A Review

Anti-inflammatory Effect and Mechanism of Duhuo Jishengtang on Rheumatoid Arthritis Rats Based on TLR2/p38 MAPK/NF-κB Signaling Pathway

Effect of Fuzitang on Proliferation of Human Rheumatoid Arthritis Synovial Fibroblast Cell Line MH7A and Expression of miR-155

Huanglian Jiedutang Regulates Inflammatory Immunity to Relieve Rheumatoid Arthritis

Related Author

YANG Haoruo

KOU Qiuai

REN Junhua

YUAN Guo

YANG Bin

ZHANG Tuanzhuang

SONG Yuan

HE Zhijun

Related Institution

Xiyuan Hospital， China Academy of Chinese Medical Sciences

Tianjin University of Traditional Chinese Medicine

Gansu Provincial Hospital of Traditional Chinese Medicine

Gansu University of Chinese Medicine

Basic Medical School， Heilongjiang University of Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰