Objective: To optimize complex purification technology of effective parts from Astragali Radix. Method: The technology of polysaccharide alcohol precipitation and removing protein were optimized by orthogonal test with the yield and content of polysaccharide in the extract as index. Purification technology of total saponins from Astragali Radix was optimized by single factor test. Result: Optimum ethanol deposition technology was as follows:3 times of 95% ethanol was added to the solution and keep still in 18 hours at 40 ℃ with the concentration of 1 ∶1(material:solution volume);The optimum technology of polysaccharide removing protein was as follows:one third volume of Sevage reagent was added into polysaccharide solution with the concentration of 15 g·L-1;Total saponin purification optimum technology was as follows:D101 macroporous resin was used

the ratio of resin to drug was 5 ∶2

eluted with 4 BV of water followed with 4 BV of 70% ethanol in D101 macroporous resin

collected ethanol eluate

evaporated. Conclusion: The polysaccharide and total saponins can be purified with the systemic method and it can be used of the full use of the material and industrial work.