Preliminary Study on Serum Pharmacochemistry of Chuanxiong Extract
|更新时间:2024-01-04
|
Preliminary Study on Serum Pharmacochemistry of Chuanxiong Extract
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 12, Pages: 96-99(2011)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2011
稿件说明:
移动端阅览
LEI Zhi-dan, LEI Zhi-jun, XIA Xin-hua. Preliminary Study on Serum Pharmacochemistry of Chuanxiong Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 96-99.
DOI:
LEI Zhi-dan, LEI Zhi-jun, XIA Xin-hua. Preliminary Study on Serum Pharmacochemistry of Chuanxiong Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 96-99.DOI:
Preliminary Study on Serum Pharmacochemistry of Chuanxiong Extract
Objective: To have a serum pharmacochemistry study on chuanxiong extract. Method: HPLC fingerprints of chuanxiong extract and serum of rats after taking the extract were established with serum pharmacochemistry method. The serum samples taken after taking chuanxiong extract were compared
the constituents absorbed into the serum after taking chuanxiong extract was determined. Result: Seven constituents migrating to the blood were detected
of which 4 were metabolites
3 were prototype constituents. Conclusion: After taking chuanxiong extract
the constituents absorbed into blood were ligustazine and ferulic acid whose serum pharmacochemistry signs could provide evidence for the pharmacological action and quality control of chuanxiong.