A Meta-analysis: Effect of Linggui Zhugan or Added Formula on Chronic Heart Failure
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A Meta-analysis: Effect of Linggui Zhugan or Added Formula on Chronic Heart Failure
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 16, Pages: 243-247(2011)
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Published:2011
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QIU Ming-liang, MAO Jing-yuan, WANG Jia-ying, et al. A Meta-analysis: Effect of Linggui Zhugan or Added Formula on Chronic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 243-247.
DOI:
QIU Ming-liang, MAO Jing-yuan, WANG Jia-ying, et al. A Meta-analysis: Effect of Linggui Zhugan or Added Formula on Chronic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 243-247.DOI:
A Meta-analysis: Effect of Linggui Zhugan or Added Formula on Chronic Heart Failure
Objective: To evaluate the clinical effect and safety of western medicine plus linggui Zhugan or added formula versus western medicine alone for chronic heart failure (CHF) patients. Method: We systematically searched the cochrane library
PubMed
EMbase
CBM
CNKI
Wanfang
VIP databases and other relevant databases and journals to identify randomized controlled trials (RCTs). According to evidence-based medicine (Cochrane) systematic evaluation method
we assessed the quality of included studies one by one
extracted valid data and undertook the Meta-analysis with RevMan 5.0.2 software. Result: Four randomized controlled trials involving 280 patients are included.The results of meta-analysis showed that western medicine plus Linggui Zhugan or added formula could improve the total effective rate .Western medicine plus Linggui Zhugan formula could increase left ventricular ejection fraction
western medicine plus added Linggui Zhugan formula .Meanwhile
only one study indicated that western medicine plus Lingguizhugan or added Formula could reduce the plasma BNP and ANP levels
respectively. Conclusion: By comparison with western medicine
western medicine plus Lingguizhugan or added formula can improve the therapeutic effects in CHF patients.