Objective: To investigate the effects of carbonized Typhae Pollen on the hemorheological parameters

clotting time and tongue presentations in acute blood-stasis model of rat. Method: The SD rats were divided into control

model

Yunnan White Drug-power

carbo power of Typhae Pollen (high

middle and low dosage

15

6

3 g·kg-1 accordingly). Except the control group

blood stasis model was established in the rest groups. The hemorheological parameters

the prothrombinase time (PT)

activated partial thromboplastin time (APTT)

thrombin time (TT)

fibrinogen (FIB) and the signs of tongue presentations were detected in these groups. Result: Carbonized Typhae Pollen in high

middle and low dosage could decrease the viscosity of whole blood (ηb) at low shear rate

erythrocyte sedime natation rate (ESR) and rigidity of erythrocyte

which increased in model rats. Carbo of Typhae Pollen of high and middle dosage could lengthen TT

PT

shorten APTT and decrease FIB

while low dosage could shorten PT and APTT. Carbo of Typhae Pollen showed therapeutical effect in hydrops and bleeding of tongue and the high dosage showed the best effect. Conclusion: Carbonized Typhae Pollen showed the effect of invigorating blood and hemostasis by ameliorating the abnormal hemorheological parameters and the signs of tongue blood stasis. Carbonized Typhae Pollen in high and middle dosage could lengthen PT and TT

which showed the dosage has two-way regulating functions on hemostasis.