Experimental Study on Metabolism and Bio-Transformation of Ginsenoside Rg by Intestinal Enzyme and Microflora in Rats
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Experimental Study on Metabolism and Bio-Transformation of Ginsenoside Rg by Intestinal Enzyme and Microflora in Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 11, Pages: 210-212(2011)
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Published:2011
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CHEN Xin-mei. Experimental Study on Metabolism and Bio-Transformation of Ginsenoside Rg by Intestinal Enzyme and Microflora in Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 210-212.
DOI:
CHEN Xin-mei. Experimental Study on Metabolism and Bio-Transformation of Ginsenoside Rg by Intestinal Enzyme and Microflora in Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 210-212.DOI:
Experimental Study on Metabolism and Bio-Transformation of Ginsenoside Rg by Intestinal Enzyme and Microflora in Rats
Objective: To investigate the effect of metabolism and bio-transformation of GRg1 by intestinal enzyme and microflora in rats. Method: The stability of GRg1 in the artificial gastric juice and intestinal juice was tested.The metabolism and bio-transformation of GRg1 administrated orally in rats were studied. Result: GRg1 was degraded totally within 2 hours in artificial gastric juice.Meanwhile
GRg1 was stable in artificial intestinal juice.GRg1 was metabolized by intestinal enzyme microflora in rats. Conclusion: GRg1 should be administrated from other routes instead of oral route in order to improve the bioavailability.
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