Objective: Studied on ultrasonic-assisted extraction of total flavonoids from Fructus Sophorae. Method: Total flavonoids were extracted by ultrasonic-assisted technique

yield of total flavonoids as the index. The optimum parameters of the technology were obtained through single-factor and orthogonal test. Result: The optimum extraction process was as follows: ethanol concentration 80%

solid-liquid ratio 1 g ∶50 mL

extracting temperature at 50 ℃

extracting for 45 min under the ultrasonic power of 250×70% W. In this optimum extracion conditions

the yield of total flavonoids was 3.04%. Conclusion: The optimum extraction process was achieved

which is suitable for industrialization with short extraction time

high efficiency

without heating.