Evaluation on Pre-Preparation of Total Saponins Extract from Bupleuri Radix
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Evaluation on Pre-Preparation of Total Saponins Extract from Bupleuri Radix
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 18, Pages: 12-15(2011)
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Published:2011
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FENG Chuan-hua, ZHANG Guo-song, LUO Xiao-jian, et al. Evaluation on Pre-Preparation of Total Saponins Extract from Bupleuri Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 12-15.
DOI:
FENG Chuan-hua, ZHANG Guo-song, LUO Xiao-jian, et al. Evaluation on Pre-Preparation of Total Saponins Extract from Bupleuri Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(18): 12-15.DOI:
Evaluation on Pre-Preparation of Total Saponins Extract from Bupleuri Radix
Objective: To study on pre-preparation of total saponins extract from Bupleuri Radix and provide a basis for rational design of dosage forms. Method: Using spectrophotometry and high performance liquid chromatography to investigate of the appraent aqueous solubility
oil-water partition coefficient
stability and preliminary gastric irritation of extracts of total saponins extract from Bupleuri Radix. Result: The appraent aqueous solubility in water was 0.145 g ·L-1.In buffer of pH 5.0
oil-water partition coefficient was 34.72; In buffer of pH 9.0
oil-water partition coefficient was 60.36
High-humidity test results didn't meet requirements;Had greater irritating. Conclusion: Appraent aqueous solubility of total saponins extract from Bupleuri Radix was small
oil-water partition coefficient in alkaline solution was greater than in acidic solution
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Medicated Serum of Bupleuri Radix Regulates HFL1 Apoptosis and Fibroblast-myofibroblast Transition via Smad3/Rheb Axis
Effect of Inoculation with Organophosphate Solubilizing Bacteria on Quality and Soil Fertility of Paris polyphylla var. yunnanensis
Meridian Tropism of Components in Bupleuri Radix Based on Nonalcoholic Steatohepatitis Model and Principal Component Analysis
Construction of Evaluating Method and Experimental Research for Targeting of Traditional Chinese Medicine Preparations Based on Supramolecular Qi Chromatography Theory
Related Author
GAO Xingxiao
HAO Min
LI Fuyan
SUN Peng
LI Da
SHEN Xiao
WU Quhui
ZHENG Lei
Related Institution
School of Pharmacy,Shandong University of TCM
School of Pharmacy, Zhejiang Chinese Medical University
Zaozhuang Hospital,Dongfang Hospital,Beijing University of Chinese Medicine/Zaozhuang Hospital of Traditional Chinese Medicine(TCM)
Hunan University of Chinese Medicine
The First Hospital of Hunan University of Chinese Medicine