Optimization of Fuyajing Effervescent Tablet Extraction Process by Central Composite Design-Response Surface Method
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Optimization of Fuyajing Effervescent Tablet Extraction Process by Central Composite Design-Response Surface Method
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 16, Pages: 37-40(2011)
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Published:2011
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LIU Xue-mei, WANG Zhi-ping, WEI Hui-xian. Optimization of Fuyajing Effervescent Tablet Extraction Process by Central Composite Design-Response Surface Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 37-40.
DOI:
LIU Xue-mei, WANG Zhi-ping, WEI Hui-xian. Optimization of Fuyajing Effervescent Tablet Extraction Process by Central Composite Design-Response Surface Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 37-40.DOI:
Optimization of Fuyajing Effervescent Tablet Extraction Process by Central Composite Design-Response Surface Method
Objective: The extraction process of Fuyajing effervescent tablet was optimized by central composite design-response surface method. Method: The main influential factors on extraction process included the quantity of ethanol
the concentration of ethanol and extraction time. The extraction conditions were evaluated by the yield of extract and the total content of polydatin and osthole. The response surface methodology was used to optimize the conditions of extraction. Result: The optimum condition of extraction was extracted 2 times for two hours with ten times amount of 60% ethanol. Conclusion: It is simple
convenient and high predictive to optimize the extraction process of Fuyajing effervescent tablet by central composite design-response surface method.
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