Recurrent oral ulcer (ROU) represents a very common but poorly understood mucosal disorder. It can occur in men and women of all ages

races and geographic regions. It is estimated that at least 1 in 5 individuals has at least once been afflicted with recurrent oral ulcer. Attacks may be precipitated by local trauma

stress

food intake

drugs

hormonal changes and vitamin and trace element deficiencies. However

to date

no principal cause has been discovered. There is no curative therapy to prevent the recurrence of ulcers

and all available therapies can only reduce the frequency or severity of the lesions. In order to provide a valuable reference for clinical treatment

in this article we collected and analyzed the reports about recurrent oral ulceration recently

and make a review of treatments for recurrent oral ulceration.