Influence and Therapeutic Effect of Qixian Tang on TNF-α and IL-8 in Patients with Ulcerative Colitis
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Influence and Therapeutic Effect of Qixian Tang on TNF-α and IL-8 in Patients with Ulcerative Colitis
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 8, Pages: 255-257(2011)
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Published:2011
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CHEN Ai-min, LIU Yong-fen, XONG Wen-wen, et al. Influence and Therapeutic Effect of Qixian Tang on TNF-α and IL-8 in Patients with Ulcerative Colitis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 255-257.
DOI:
CHEN Ai-min, LIU Yong-fen, XONG Wen-wen, et al. Influence and Therapeutic Effect of Qixian Tang on TNF-α and IL-8 in Patients with Ulcerative Colitis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 255-257.DOI:
Influence and Therapeutic Effect of Qixian Tang on TNF-α and IL-8 in Patients with Ulcerative Colitis
Objective: To investigate the effects of Qixiantang on TNF-α and IL-8 in patients with ulcerative colitis (UC). Method: Fifty patients with UC were divided into therapy group (25 patients treated with Qixiantang) and control group (25 patients treated with sulfasalazine and dexamethasone).TNF-α and IL-8 in serum were detected by ELISA for all patients before and after treatment
and compared with 25 healthy volunteers. Result: Creative effects in therapy group was obviously better than that in control group
the difference was significance (P<0.05).After treatment
compared with control group
therapy group had the lower plasma levels of TNF-α and IL-8 (P<0.05). Conclusion: Qixiantang is effective for patients with UC. The down regulation of the expressions of TNF-α and IL-8 in serum may be one of the therapeutic mechanism.
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