The Study on the Content of the Saponins in the Different Processed Products of Radix Polygalae

LIN Jing-kai; YAN Xiao-ping; GUAN Shi-jie; LI Li

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The Study on the Content of the Saponins in the Different Processed Products of Radix Polygalae

更新时间：2024-01-04

- The Study on the Content of the Saponins in the Different Processed Products of Radix Polygalae
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 11, Pages: 89-91(2011)
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- Published：2011
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LIN Jing-kai, YAN Xiao-ping, GUAN Shi-jie, et al. The Study on the Content of the Saponins in the Different Processed Products of Radix Polygalae[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 89-91.
DOI：

LIN Jing-kai, YAN Xiao-ping, GUAN Shi-jie, et al. The Study on the Content of the Saponins in the Different Processed Products of Radix Polygalae[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 89-91. DOI：

摘要

目的: 研究生远志、制远志、蜜远志中皂苷类成分含量的差异。方法: 以远志酸和远志皂苷元含量为指标对3种炮制品进行HPLC测定。色谱柱为Agilent ZORBAX SB-C18(4.6 mm×250 mm

5 μm)

流动相为乙腈-0.1%磷酸(41 ∶59);检测波长210 nm;流速1.0 mL ·min-1

柱温25 ℃。结果: 远志酸含量和远志皂苷元含量

均为制远志＞生远志＞蜜远志。结论: 不同炮制方法能改变远志皂苷类成分的含量

蜜远志的远志酸含量与远志皂苷元含量均低于生远志与制远志。

Abstract

Objective: To analyze the difference of the saponins in the different processed products of Radix Polygalae(crude Radix Polygalae

licorice And Honey Processed Radix Polygalae). Method: The content of polygalacic acid and senegenin in the different processed products of Radix Polygalae was determine by HPLC using an Agilent ZORBAX SB-C18(4.6 mm×250 mm

5 μm) with acetonitrile-0.1% phosphoric acid (41 ∶59) as the mobile phase; the flow rate was 1.0 mL ·min-1; temperatures was 25 ℃ and UV detection wavelength at 210 nm. Result: The order of the content of polygalacic acid and senegenin (from higher to lower) was:crude Radix Polygalae

licorice processed Radix Polygalae

honey processed Radix Polygalae. Conclusion: The different process method has some effects on the content of saponins in Radix Polygalae. The content of polygalacic acid and senegenin in honey processed Radix Polygalae was the lowest. The LD50 experiment result suggests that honey processed can reduce the toxic composition of crude Radix Polygalae .

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