Optimization of Extraction Technology of Total Flavonoids from by Response Surface Method
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Optimization of Extraction Technology of Total Flavonoids from by Response Surface Method
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 16, Pages: 29-32(2011)
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Published:2011
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ZHOU Xiang-jun, GAO Yi-xia, ZHANG Xia. Optimization of Extraction Technology of Total Flavonoids from by Response Surface Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 29-32.
DOI:
ZHOU Xiang-jun, GAO Yi-xia, ZHANG Xia. Optimization of Extraction Technology of Total Flavonoids from by Response Surface Method[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(16): 29-32.DOI:
Optimization of Extraction Technology of Total Flavonoids from by Response Surface Method
Objective: Response surface analysis methodology(RSM) was used for optimizing the extraction technology of total flavonoids from Hemerocallis citrina. Method: On the basis of single-factor tests
extraction temperature
extraction time
solid-liquid ratio and ethanol concentration were selected as influencing factors during extraction. Box-Behnken design was used to establish mathematical model. Result: The optimum conditions for total flavonoids were extraction time 180 min
extraction temperature 75 ℃
ethanol concentration 90%
solid-liquid ratio 1∶35. The predicted extraction yield of total flavonoids was 0.571%
and the verification 0.581%
with relative error of 1.32%. Conclusion: The optimized extraction technology was stable
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