Effect of Tongmai Tangyanming Capsule on Levels of Vascular EndothelialGrowth Factor in Patients with Non-proliferative Diabetic Retinopathy
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Effect of Tongmai Tangyanming Capsule on Levels of Vascular EndothelialGrowth Factor in Patients with Non-proliferative Diabetic Retinopathy
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 12, Pages: 229-231(2011)
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Published:2011
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XU Han-song, KONG De-ming, XIANG Hui. Effect of Tongmai Tangyanming Capsule on Levels of Vascular EndothelialGrowth Factor in Patients with Non-proliferative Diabetic Retinopathy[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 229-231.
DOI:
XU Han-song, KONG De-ming, XIANG Hui. Effect of Tongmai Tangyanming Capsule on Levels of Vascular EndothelialGrowth Factor in Patients with Non-proliferative Diabetic Retinopathy[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 229-231.DOI:
Effect of Tongmai Tangyanming Capsule on Levels of Vascular EndothelialGrowth Factor in Patients with Non-proliferative Diabetic Retinopathy
Objective: To observe the effects and possible mechanism of Tongmai Tangyanming capsule on the levels of vascular endothelial growth factor(VEGF) in patients with non-proliferative diabetic retinopathy(DR). Method: Sixty-eight DR patients were randomly divided into 36 of tongmai tangyanming capsule treatment group and 32 of control group.30 of normal subject as normal group.The levels of VEGF were measured in three group pre and post treatment. Result: Serum levels of VEGF in DR group were significantly higher than those of the normal group (P<0.01).after 8 weeks treatment
when comparing with that before treatment
the levels of VEGF were decreased(P<0.01); Compared with control group
the levels of VEGF in the treated group decreased significantly(P<0.01). Conclusion: Tongmai tangyanming capsule can effectively decrease the levels of VEGF in DR patients
so that partly suppresses the development of diabetic retinopathy.
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