Study on Preparation Technology of Gutong Film Coating Tablets

GAO Hua-hong; FU Jian-wu; ZENG Wen-xue

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Study on Preparation Technology of Gutong Film Coating Tablets

更新时间：2024-01-04

- Study on Preparation Technology of Gutong Film Coating Tablets
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 8, Pages: 41-43(2011)
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- Published：2011
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GAO Hua-hong, FU Jian-wu, ZENG Wen-xue. Study on Preparation Technology of Gutong Film Coating Tablets[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 41-43.
DOI：

GAO Hua-hong, FU Jian-wu, ZENG Wen-xue. Study on Preparation Technology of Gutong Film Coating Tablets[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 41-43. DOI：

摘要

目的: 研究骨通薄膜衣片的处方组成和制备工艺。方法: 以颗粒性状、制粒难度、休止角、片面光洁度、硬度、崩解时限为指标

单因素法优选片剂处方。结果: 按照浸膏粉-淀粉-乳糖-微粉硅胶(1 ∶0.5 ∶0.4 ∶0.1)的比例混合

85%乙醇制粒

压片、包薄膜衣。结论: 骨通薄膜衣片处方合理

工艺简便易行

可达到生产要求。

Abstract

Objective: To study formulation and preparation of Gutong film coating tablets. Method: The single-factor method was taken to optimize the pharmaceutical formulations

the content was selected by granule properties

granulating difficulty

angle of repose

degree of surface smoothness

hardness and disintegration. Result: The optimum process was as follows:the weight proportion of dry extraction to starch

lactose and silica powder was 1 ∶0.5 ∶0.4 ∶0.1; the wetting agent was 85% alcohol; through wet-granulating

tabletting and film coating

the Gutong tablets were prepared successfully. Conclusion: The formulation of Gutong film coating tablets is reasonable and the process technical is simple and feasible

which conforms to the general requirements of production.

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