Optimization of Extract Technology of Radix Linderae from Dangwu Dispersible Tablet by Single-factor Test and Orthogonal Experiment

CHEN Jin-yu; YIN Rong-li; CHEN Hai-ting; LI Dong-fen; WANG Bao-cai; MEI Ru-huai

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Optimization of Extract Technology of Radix Linderae from Dangwu Dispersible Tablet by Single-factor Test and Orthogonal Experiment

更新时间：2024-01-04

- Optimization of Extract Technology of Radix Linderae from Dangwu Dispersible Tablet by Single-factor Test and Orthogonal Experiment
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 6, Pages: 33-35(2011)
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- Published：2011
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CHEN Jin-yu, YIN Rong-li, CHEN Hai-ting, et al. Optimization of Extract Technology of Radix Linderae from Dangwu Dispersible Tablet by Single-factor Test and Orthogonal Experiment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 33-35.
DOI：

CHEN Jin-yu, YIN Rong-li, CHEN Hai-ting, et al. Optimization of Extract Technology of Radix Linderae from Dangwu Dispersible Tablet by Single-factor Test and Orthogonal Experiment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 33-35. DOI：

摘要

目的: 探讨当乌分散片中的药材乌药的最佳提取工艺。方法: 以乌药醚内酯质量分数为考察指标

选择提取方法、提取溶剂、提取次数

用单因素考察方法确定因素水平;再以乙醇体积分数、料液比、提取温度、提取时间为考察因素

以乌药醚内酯质量分数为指标

同时考虑收膏率

用正交试验方法对其最佳工艺进行优化。结果: 最佳提取工艺:超声提取

90%乙醇

50 ℃的提取温度

提取2次

每次20 min

每次6倍量的提取溶剂。结论: 采用超声提取法具有提取快速

有效成分提取率高等优点

此工艺合理可行。

Abstract

Objective: To optimize the optional extraction method of Radix Linderae from Dangwu Dispersible Tablet. Method: Extracting method

extraction solvent and extraction times were selected to determine the factors and levels by single-factor test method with the content of linderane as index. Then content of linderane was used as index to evaluate the technologies based on orthogonal design

considering ointment rate at the same time

in which 4 factors considered were the concentration of ethanol

solvent consumption

extraction temperature and extracting time. Result: The optimum extraction processes was ultrasonic extraction technique

50 ℃

adding 6 times amount of 90% ethanol

extracting for two times with 20 min each time. Conclusion: The method has the advantage of speediness

higher extraction rate etc. This process is stable and reliable.

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Related Institution

Faculty of Medicine,Beihua University

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