Research Progress in Chemical Components, Pharmacological Effectiveness and Toxicity of Radix et Rhizoma Sophorae tonkinensis
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Research Progress in Chemical Components, Pharmacological Effectiveness and Toxicity of Radix et Rhizoma Sophorae tonkinensis
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 4, Pages: 229-232(2011)
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Published:2011
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WANG Jun-ming, CUI Ying. Research Progress in Chemical Components, Pharmacological Effectiveness and Toxicity of Radix et Rhizoma Sophorae tonkinensis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 229-232.
DOI:
WANG Jun-ming, CUI Ying. Research Progress in Chemical Components, Pharmacological Effectiveness and Toxicity of Radix et Rhizoma Sophorae tonkinensis[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 229-232.DOI:
Research Progress in Chemical Components, Pharmacological Effectiveness and Toxicity of Radix et Rhizoma Sophorae tonkinensis
Objective: To introduce the research progress in chemical components
pharmacological actions and toxicity of Radix et Rhizoma Sophorae tonkinensis . Method: The relevant information and references were looked through
and further analyzed and reviewed. Result: Up to now
the chemical components isolated from S. tonkinensis include mainly flavonoids
alkaloids
polysaccharides
etc. Pharmacological references show that it has effects on antitumor
anti-inflammation
antimicrobial
hepatoprotection
immune stimulation
antiarrhythmia
antihypertension and so on. However
it may also induce toxicity such as hepatotoxicity
neurotoxicity
and gastrointestinal side effects. Conclusion: We should carry out further studies on mechanism-based antitumor activity and toxicity for the radix et rhizoma S. tonkinensis
to determine the safe and effective therapeutic window
and even to explore detoxification and enhancement actions by combing other medicines with it so to ensure its safe and effectiveness in clinic application.