Effect of Jinkui Shenqi Pill on Sperm Quality and Renal Function in Rats Adenine-induced Infertility
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Effect of Jinkui Shenqi Pill on Sperm Quality and Renal Function in Rats Adenine-induced Infertility
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 8, Pages: 184-186(2011)
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Published:2011
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MA Liang, LIU Hua-jian, NAN Ya-yun, et al. Effect of Jinkui Shenqi Pill on Sperm Quality and Renal Function in Rats Adenine-induced Infertility[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 184-186.
DOI:
MA Liang, LIU Hua-jian, NAN Ya-yun, et al. Effect of Jinkui Shenqi Pill on Sperm Quality and Renal Function in Rats Adenine-induced Infertility[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(8): 184-186.DOI:
Effect of Jinkui Shenqi Pill on Sperm Quality and Renal Function in Rats Adenine-induced Infertility
Objective: To observe the influence of Jinkui Shenqi Pill on sperm quality and renal function in rats with adenine-induced infertility. Method: Thirty adult male SD rats were randomly divided into Jinkui Shenqi Pill group
model group and control group. Sperm qualities of experimental rats were detected by automatic sperm quality analyzer
and contents of testosterone(T)
estradiol(E2)
luteinizing hormone(LH) and follicle-stimulating hormone(FSH) were measured by radioimmunoassay. Contents of BUN and Scr were ested by automatic biochemical analyzer. Renal tissue was observed by optical microscope. Testis was observed by transmission electron microscopy. Result : Jinkui Shenqi Pill could significantly improve symptoms of Shen-yang deficiency in adenine-induced infertility rats
and it could improve the sperm quality
including sperm density
sperm motility and sperm activity. It could increase content of T obviously
lower contents of E2
LH and FSH
lower contents of BUN and Scr. And it can better the damaged kidney tissue in model rats. Conclusion : Jinkui Shenqi pill can improve sperm quality significantly and improve function of kidney. And the mechanism of improving sperm quality may be related to the increase in content of T by stimulating the interstitial cells and lowering level of E2.
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Related Institution
Graduate School, Hebei University of Chinese Medicine
The First Affiliated Hospital of Hebei University of Chinese Medicine,Hebei Provincial Hospital of Traditional Chinese Medicine
Affiliated Hospital of Hebei University of Chinese Medicine/Hebei Provincial Hospital of Traditional Chinese Medicine
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