Study on Formulation Technology of Simotang Dropping Pills

LIU Ling-an; YANG Hua; GAO Xiao-hui; LIU Dong-wen; DENG Yi-de; YI Yue-neng

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Study on Formulation Technology of Simotang Dropping Pills

更新时间：2024-01-04

- Study on Formulation Technology of Simotang Dropping Pills
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 3, Pages: 46-48(2011)
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- Published：2011
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LIU Ling-an, YANG Hua, GAO Xiao-hui, et al. Study on Formulation Technology of Simotang Dropping Pills[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 46-48.
DOI：

LIU Ling-an, YANG Hua, GAO Xiao-hui, et al. Study on Formulation Technology of Simotang Dropping Pills[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 46-48. DOI：

摘要

目的 :研究四磨汤滴丸最佳成型工艺。方法 :采用单因素及正交试验进行优选

以丸重变异、崩解时限、外观质量等为指标

考察滴制温度、滴速、滴头口径等因素的影响

优化成型工艺条件。结果 :最佳成型工艺为滴制温度75 ℃

滴速30~40滴/min

滴头口径2.0 mm/5.0 mm。结论: 成型工艺稳定可行

适宜工业化生产。

Abstract

Objective: To establish the optimized preparation of Simotang dropping pills. Method : The optimum extraction process was selected with Single-factor test and orthogonal

taking difference of pill mass

dissolution and the shape of pill as indicators

and through examing the dropping temperature

dropping speed and external diameter of burette to select the best dropping conditions. Result: The best dropping conditions was that the dropping temperature was at 75 ℃

dropping speed was 30 to 40 drops per minutes

internal and external diameter of burette are 2.0 mm and 5.0 mm. Conclusion: The formulation technology is suitable for industrial production.

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Related Institution

School of Chinese Meteria Medica,Beijing University of Chinese Medicine

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