Preparation and Evaluation of Baicalin Microcapsule
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Preparation and Evaluation of Baicalin Microcapsule
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 11, Pages: 33-35(2011)
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Published:2011
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CUI Ming-yu, WANG Yan, SUN Zhi-wei, et al. Preparation and Evaluation of Baicalin Microcapsule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 33-35.
DOI:
CUI Ming-yu, WANG Yan, SUN Zhi-wei, et al. Preparation and Evaluation of Baicalin Microcapsule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(11): 33-35.DOI:
Preparation and Evaluation of Baicalin Microcapsule
Objective: To study the preparation method for baicalin microcapsule using gelatin gum as sealing materials. Method: Baicalin microcapsule was prepared by simple coacervation method. The uniform design was adopted to optimize the preparation procedure with drug loading as evaluation indexes. Result: The optimum preparation technique of baicalin microcapsule was: the ratio of core material to coating material was 1 ∶2; the temperature of encapsulation was at 45 ℃ and the stirring speed was 550 r ·min-1. Conclusion: The results showed that baicalin microcapsule had appropriate diameter
distribution of microcapsule particles size and the dissolution meets the requirements.
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