Objective: To establish the method of dissolution test for Xuesaitong Dispersible Tablets. Method: The small cup method was used with distilled water as dissolution medium at a rotate speed of 50r ·min- 1

Paddle method was used and the dissolving time was 60 minutes. The dissolution rate was determined by HPLC-ELSD. Result: The cumulate dissolution rate of Xuesaitong Dispersible Tablets had little difference in and between batches. The cumulate dissolution percentage of Xuesaitong Dispersible Tablets tended to be stable after 30 minutes

and the dissolution parameters T50 and Td of Xuesaitong Dispersible Tablets were 3.58min

5.99min

Xuesaitong capsules and tablets dissolution parameters T50 and Td were 13.39

25.42

26.53

56.77 min respectively. Conclusion: The method established is simple

accurate and repeatable for the quality control of Xuesaitong Dispersible Tablets. The dissolution of Xuesaitong Dispersible Tablets was quicker than that of the marketed capsules and that of the common tablets.