Prescription Compatibility Effect on Absorption of Major Components in Yanhusuo Extract
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Prescription Compatibility Effect on Absorption of Major Components in Yanhusuo Extract
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 6, Pages: 203-205(2011)
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Published:2011
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LIN Li, LIU Jian-xun, ZHANG Ying, et al. Prescription Compatibility Effect on Absorption of Major Components in Yanhusuo Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 203-205.
DOI:
LIN Li, LIU Jian-xun, ZHANG Ying, et al. Prescription Compatibility Effect on Absorption of Major Components in Yanhusuo Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 203-205.DOI:
Prescription Compatibility Effect on Absorption of Major Components in Yanhusuo Extract
An improved everted gut sac method was applied to the prescription compatibility effect on absorption of the major components in Rhizoma Coridalis extracts. With the separation and detection
tetrahydropalmatine(THP) and dehydrocorydaline(DHC) were quantified by HPLC-UV. The standard curves of THP and DHC were lineary over the concentration range of 0.29-46.4 and 0.09-22.7 g ·mL-1 respectively. The extraction recovery of both compounds were 95%-100%. The precisions
the accuracy and the stability all met the requirements. The contents of THP did not show difference before and after compatible prescription administrated
where the DHC had a significant increase in the same process. The results revealed that DHC might lead to an increasing pharmacological effect after prescription compatibility.
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Related Author
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DU Hanqian
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XU Ying
YANG Yibo
Related Institution
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
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Key Laboratory of Resource and Compound Prescription of Traditional Chinese Medicine, Ministry of Education,Hubei University of Chinese Medicine
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School of Chinese Pharmacy,Beijing University of Traditional Chinese Medicine