Experiment Study on Wound Healing Mechanisms of Jintangbao Spray for Treating Burn Injury
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Experiment Study on Wound Healing Mechanisms of Jintangbao Spray for Treating Burn Injury
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 7, Pages: 186-189(2011)
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Published:2011
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LUO Xian-qin, LIU Jian-yi, HUANG Si-xing, et al. Experiment Study on Wound Healing Mechanisms of Jintangbao Spray for Treating Burn Injury[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(7): 186-189.
DOI:
LUO Xian-qin, LIU Jian-yi, HUANG Si-xing, et al. Experiment Study on Wound Healing Mechanisms of Jintangbao Spray for Treating Burn Injury[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(7): 186-189.DOI:
Experiment Study on Wound Healing Mechanisms of Jintangbao Spray for Treating Burn Injury
Objective: To investigate the wound healing effect of Jintangbao Spray for promoting superficial second degrees burn
as well as anti-inflammatory and analgesic actions. Method: The effect of wound healing was investigated through superficial second degrees burn model in rats and feet burn model in mice. Anti-inflammatory effect was investigated through carrageenan-induced swelling of rat toes. Analgesic effect was investigated through formaldehyde-induced pain in mice. Result: Compared with the model group
Jintangbao Spray could remarkly promote healing of cutis in the trauma with superficial second degrees burn in rats. The pathomorphological evidences of hepatic tissue showed thatJintangbao Spray could remarkably repair cutaneous epidermis injury and the disorganized collagen fiber-bundle of dermis
and promote dermal follicle proliferation
as well as lighten inflammatory cell intiltration. It could significantly reduce water content in the feet burn model in mice
inhibit the carrageenan-induced swelling of rat toes and lighten the pain caused by formaldehyde in mice. Conclusion: Jintangbao Spray can remarkly promote healing of cutis in the trauma and has anti-inflammatory and analgesic effects
and the evidences provide the basis for clinical application of the medicine.
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