Objective: To screen out the optimum technology for purification of total anthraquinones from Radix et Rhizoma Rhei. Method: Adsorption performance and desorption capacity were compared with different types of macroporous resin with the content of total anthraquinones as the target

so as to select the appropriate resin category. Thus

specific parameters of greatest sample volume

sample speed and elution solution etc were selected from resin purification technology by single-factor study. Result: The technology for AB-8 macroporous resin to purify total anthraquinones from Rheum could not only guarantee the elution rate of 82.96% of major effective indigent

but also decrease the solid content from 38.03% to 12.23% at the same time. Conclusion: AB-8 had a good effect on the adsorption of total anthraquinones from Rheum and has a good appliccation prospect.