Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 6, Pages: 197-199(2011)
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Published:2011
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QUAN Ji-hua, JIN Yan-hua, YIN Xue-zhe. Antioxidative Effect of Ethanol Extract of [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 197-199.
DOI:
QUAN Ji-hua, JIN Yan-hua, YIN Xue-zhe. Antioxidative Effect of Ethanol Extract of [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 197-199.DOI:
Objective: To study the antioxidative effect of ethanol extract of Rhaponticum uniflorum. Method : The effect of R.uniflorum ethanol extract on the total antioxidant capacity of liver was determined by ferric reducing method
and the anti-lipid peroxidative activity was detected by thiobarbituric acid (TBA) method. Result :R. uniflorum ethanol extract concentration-dependently elevated the total antioxidant capacity of liver homogenate
inhibited the lipid peroxidation of liver homogenate induced by H2O2
·OH and Fe2+ with the IC50s of 56.4
144.2 and 355.6 mg ·L-1
respectively
and inhibited the lipid peroxidation of liver mitochondria induced by H2O2 and Fe2+ with the IC50s of 781 and 36.3 mg ·L-1
respectively. Conclusion: The ethanol extract of R. uniflorum has an antioxidative effect in vitro.
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