Objective: To investigate the fingerprint for methanol extraction of Muxiang Shunqi pills by HPLC-UV. Method: The samples were separated with an Agilent Zorbax Eclipse XDB C18 reversed-phase column(4.6 mm×150 mm

5 μm) by linear gradient elution using water-acetonitrile as mobile phase; the flow rate was 1 mL ·min-1 and the detection wavelength was set at 280 nm

225 nm(rosa banksiae); the column temperature was set at 35 ℃. Muxiang Shunqi pills from different pharmaceutical company were compared and the individual crude drugs were analyzed. Result: Honokiol was linear in the range of 104-520 mg ·L-1

Y=70 580X+1.187 5. r=0.999 7; RSD of all relative retention time and relative peak area achieved good results

the precision test and stability test satisfied the requirements and repeatability test was less than 1% and 3% respectively. Conclusion: The quality of Muxiang Shunqi pills is obviously different; one of the main reasons of such state is the quality of crude drugs.