Effects of Huangjin Capsule on Insulin Resistance in Type 2 Diabetic Rats
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Effects of Huangjin Capsule on Insulin Resistance in Type 2 Diabetic Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 3, Pages: 199-201(2011)
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Published:2011
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YU Chen-zu, AN Xiao-ping, KANG Xue-dong, et al. Effects of Huangjin Capsule on Insulin Resistance in Type 2 Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 199-201.
DOI:
YU Chen-zu, AN Xiao-ping, KANG Xue-dong, et al. Effects of Huangjin Capsule on Insulin Resistance in Type 2 Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 199-201.DOI:
Effects of Huangjin Capsule on Insulin Resistance in Type 2 Diabetic Rats
Objective: To investigate the effects of Huangjin capsule on insulin resistance in type 2 diabetic rats and the primary pharmacological mechanism. Method: The model of type 2 diabetic-insulin-resistant rats (T\-2DIRR) was made through intraperitonea injection of lower dosage of streptozocin(30 mg ·kg-1) and high caloric diet (abounded with sugar & fat)
the effects of Huangjin capsule on weight
blood and serum contents of glucose
TC
TG
HDL-C
observed in the model rats. Result: Huang jin capsule lowered significantly fasting blood glucose (FBG) and improved HDL-C; and reduced the TC
TG in T\-2DM
IR
and reduced the concentration of insulin in hyperinsulinemia
and potentiated ISI (P<0.01) in T\-2DM
IR. Conclusion: In the experiment with type 2 diabetic-insulin-resistant rats
huang jin capsule can lower fasting blood glucose (FBG) and reduce level of TC