Effect of Extracts from  on Hyperglycemia

QIN Zhen-lin; WEI Hai-ying; LIAO Dong-yan; LI Xue-jian

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Effect of Extracts from on Hyperglycemia

更新时间：2024-09-23

- Effect of Extracts from on Hyperglycemia
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 4, Pages: 108-110(2011)
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- Published：2011
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QIN Zhen-lin, WEI Hai-ying, LIAO Dong-yan, et al. Effect of Extracts from on Hyperglycemia[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 108-110.
DOI：

QIN Zhen-lin, WEI Hai-ying, LIAO Dong-yan, et al. Effect of Extracts from on Hyperglycemia[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 108-110. DOI：

摘要

目的 :研究瑶药柚子枫提取物的降血糖作用。方法: 采用四氧嘧啶所致小鼠糖尿病模型和葡萄糖所致高血糖小鼠模型

ig给药7 d后

测定血糖水平。结果: 柚子枫水提醇沉上清液提取物(A1)和水提醇沉沉淀物(A2)ig 5

20 g ·kg-1对四氧嘧啶糖尿病小鼠血糖升高有明显抑制作用

70%醇提物(B)对高血糖值降低作用不明显。A1

A2在ip葡萄糖后0.5

2 h

对葡萄糖引起高血糖小鼠血糖升高有明显降低作用

B在5~20 g ·kg-1剂量下1

2 h对高血糖值降低作用不明显。结论: A1

A2对2种高血糖模型作用效果一致

表现出降血糖作用;B无显著降糖作用。

Abstract

Objective: To investigate the effect of extracts from Pothos chinensis (Raf.)Merr.on hyperglycemia. Method: Experimental observation was performed by using diabetic mice induced by alloxan and glucose injection.The mices were randomly divided into the control and treated group to detect blood glucose level respectively. Result: Both the extract of water extracting-alcohol precipitating solution of P.chinensis (A1) and extract of water extracting-alcohol precipitating sediments (A2) exhibited considerable beneficial effect on lowering the abnormal blood glucose level induced by alloxan in mice.The 70% alcohol extract (B) showed little effect.Both A1 and A2 reduced significantly the high blood glucose level induced by glucose injection in mice after 0.5

1 and 2 hours. Conclusion: Both A1 and A2 exhibited the same beneficial effect on the two kinds of diabetic mice model

suggesting a considerable hypoglycemic effect.B has no obvious effect on diabetic mice model.

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Related Author

TAO Aien

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Related Institution

Medical School， Lijiang Culture and Tourism College

Guangxi Zhuang Yao Medicine Engineering Technology Research Center， Guangxi University of Chinese Medicine

Faculty of Chinese Medicine Science，Guangxi University of Chinese Medicine

Jiangxi Institute for Drug Control, Jiangxi Province Engineering Research Center of Drug and Medical Device Quality

Jiangxi Food and Drug Administration

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