Objective: To estalish an accurate method for the determination of baicalin in Qinqiao Kanggan granules. Method: Diamonsil C18(4.6 mm×250 mm

5 μm)column in an oven at 30 ℃was need

with a mobile phase consisting of mathanol-0.1% phosphoric acid(48 ∶52) and a UV detector at 280 nm

the flow rate was 1.0 mL ·min-1. Result: The linear ranges of baicalin was 0.49-2.46μg(r=0.999 9).The RSD of measurement precision test was 0.25%; The average recovery was 100.54% (RSD 1.89%

n=5). Conclusion: The method was simple and accurate

and can be used for the quality control of Qinqiao Kanggan granules.