Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet
|更新时间:2024-09-23
|
Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 18, Pages: 166-168(2010)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2010
稿件说明:
移动端阅览
YU Yong-jun, LIU Qing-xin, ZHANG Qiu-yu, et al. Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 166-168.
DOI:
YU Yong-jun, LIU Qing-xin, ZHANG Qiu-yu, et al. Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 166-168.DOI:
Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet
Objective: To observe the effects of Quzhi Baogan Granules on the rat’s fatty liver. Method: The rat’s fatty liver was induced by high fat diet. The different groups were given different drugs
to observe the efficacy of Quzhi Baogan Granules on the rat’s fatty liver
meanwhile to investigate the mechanism of the granules on the rat’s fatty liver. Result: Compared with blank control group
liver tissue CHO
TG levels in the models were increased significantly(P<0.01)
serum AST
ALT were significantly increased(P<0.01). Pathological investigation showed that liver cell steatosis was took place associated with cell injury and necrosis. Compared with model group
the liver tissue CHO
TG levels in the Quzhi Baogan high-dose group
mid-dose group
low-dose group were decreased obviously( P <0.01 or P <0.05)
the serum AST
ALT were decreased obviously( P <0.01 or P <0.05)
meanwhile the liver injury were alleviated. Conclusion: Quzhi Baogan Granules can reduce liver cell injury through the antioxidant mechanism
it can prevent and treat the rat’s fatty liver induced by high fat diet.
Experimental Study of Quzhi Baogan Granules on Rat’s Fatty Liver Induced by High Fat Diet
Effect of Coptidis Rhizoma-Fermentum Rubrumon Non-Alcoholic Fatty Liver Disease in Mice Based on Nrf2/GPX4 Ferroptosis Axis
Flos Puerariae,Hoveniae Semen and Their Combinations Treat Oxidative Stress in Mice with Acute Alcoholic Liver Injury via Keap1/Nrf2/ARE Signaling Pathway
Intervention Effect of New Chinese Herbal Prescription Selected by Data Mining Against Decreased Ovarian Reserve in Rats
Effect of Adjuvant Therapy of Huayu Pills on Neurological Recovery of Patients with Acute Cerebral Infarction