Study on the Quality Control Standard of Huoxue Yangyin Granules

CHEN Shi-cui; JU Jian-ming

您当前的位置：

首页 >

文章列表页 >

Study on the Quality Control Standard of Huoxue Yangyin Granules

更新时间：2024-01-04

- Study on the Quality Control Standard of Huoxue Yangyin Granules
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 17, Issue 7, Pages: 65-67(2011)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2011
- 稿件说明：
移动端阅览
CHEN Shi-cui, JU Jian-ming. Study on the Quality Control Standard of Huoxue Yangyin Granules[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(7): 65-67.
DOI：

CHEN Shi-cui, JU Jian-ming. Study on the Quality Control Standard of Huoxue Yangyin Granules[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(7): 65-67. DOI：

摘要

目的: 建立活血养阴颗粒的质量标准。方法: 采用薄层色谱法对活血养阴颗粒中的葛根、益母草进行定性鉴别;采用HPLC对制剂中葛根素进行了含量测定

高效液相色谱条件Alltima C18柱 (4.6 mm×250 mm

5 μm)

流动相甲醇-0.3%磷酸溶液(26 ∶74)

流速1.0 mL ·min-1

检测波长250 nm

柱温35 ℃

以外标法计算含量。结果: TLC色谱中能检出葛根、益母草;高效液相色谱测定葛根素在0.041 8~1.002 2 μg呈良好的线性关系

r=0.999 9

平均回收率 99.4%

RSD 1.4%(n=6)。结论: 该法可准确地进行定性、定量

可有效地控制活血养阴颗粒的质量。

Abstract

Objective: To establish the quality standard of Huoxue Yangyin granules composed of Herb Leonuri

Radix Puerariae Lobatae. Method: The quality of each raw material was identified by TLC. The quantity of the preparation was conducted by HPLC and the method was developed with the condition as follows: Alltima C18 (4.6 mm×250 mm

5 μm)

mobile phase methanol-0.3% phosphoric acid (26 ∶74)

the temperature of column 35 ℃

flow rate 1.0 mL ·min-1

calculating the content with external standard method. Result: Herb Leonuri

Radix Puerariae Lobatae could be detected by TLC. Puerarin was linear in a range of 0.041 8~1.002 2 μg (r=0.999 9). The average recovery was 99.4%

and RSD was 1.4% (n=6). Conclusion: This method is simple

reliable

accurate

and can be used to control the quality of Huoxue Yangyin granules.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Standard of Quality Control of Mailuotong Jiaonang

Study on Quality Standard of Zhifukang Capsule

Studies on Qualitative and Quantitative Methods of Liangge Pills

Influence of dfferent producing area on quality of Venenum bufonis

Studies on the Quality standard of Bimintong Capsule

Related Author

TAN Qin

SHEN Ting

JIN Fang

GUO Qing

YAO Zhong-qing

LI Man-ling

FENG Wei-hong

SHI Tao1

Related Institution

Hubei Institute for Food and Drug Control

Shanxi Renyuantang Pharmaceutical Co.,Ltd.

Shanxi University of Traditional Chinese Medicine

Natural Pharmaceutical R&D

修正药业长春高新制药有限公司

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰